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For Drug Development:
Whole Cell In Silico Molecular Profiling -> targeted
high through put profiling - True Molecular Mining
Lower attrition rates
Faster development time line
Overall Cost reduction
CHEMSAS� Advantages:
Rapid prototyping of custom applications
Exclusive licensing of custom applications
Confidentiality assured
The In Silico Drug Development Cycle
| Step | Time Line |
| In Silico Drug Discovery | 1-2 WEEKS |
| Drug Synthesis | 2-3 months |
| Confirmatory Tests | 2-3 months |
| PK/Tox Testing | 9-12 months |
| Our Development Cycle to Investigational New Drug Status | ~18 months |
| Industry Cycle | 3-5 years |
SUMMARY:
CHEMSAS� can be used by pharmaceutical companies to address the realities noted above in several areas:
- To profile new molecules for biological activity such that molecules more likely to have useful biological activity are entered into the drug development process.
- To profile existing molecules (e.g. currently available pharmaceutical and natural products) for novel activities.
- To profile "soups" of compounds such as herbal remedies or other natural products to identify the likely active components.
- To mine large databases of molecules to find molecules likely to have useful biological activities (i.e., molecular mining).
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